LAMP1 anticorps (Elab Fluor®700)

N° du produit ABIN7566893

L’anticorps Souris Monoclonal anti-LAMP1 a été validé pour FACS. Il convient pour détecter LAMP1 dans des échantillons de Humain.

Aperçu rapide pour LAMP1 anticorps (Elab Fluor®700) (ABIN7566893)

Antigène: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LAMP1 est conjugé à/à la Elab Fluor®700

Application: Flow Cytometry (FACS)

Clone: H4A3

Détail du produit anti-LAMP1 anticorps (Elab Fluor®700)

Fonction: Elab Fluor®700 Anti-Human CD107a/LAMP-1 Antibody[H4A3]

Isotype: IgG

Information d'application

Indications d'application: Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.

Commentaires:

Matching Isotype Control: E-AB-F09792M1

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Stock: 4 °C

Stockage commentaire: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Date de péremption: 12 months

Détails sur LAMP1

Antigène: LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

Autre désignation: CD107a/LAMP-1

Sujet: LAMP-1, LGP-120,Lysosome-Associated Membrane Protein 1,CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.

ID gène: 3916

UniProt: P11279

Pathways: Autophagy